San Francisco Infectious Diseases Research Center

The San Francisco Infectious Diseases Research Center (SF IDRC) is a multi-purpose research program implementing NIH- and pharma-funded clinical trials. Our center conducts cutting-edge clinical trials to improve the lives of people living with HIV and other infectious diseases.
Our mission is to investigate the most effective strategies to treat, prevent, and cure infectious diseases, including:
- HIV
- HIV-related complications
- Viral hepatitis
- Sexually transmitted infections
- Emerging infectious diseases, including MPOX and novel respiratory pathogens
Based in the new UCSF Pride Hall building on the Zuckerberg San Francisco General campus, SF IDRC is home to the UCSF NIH-funded UCSF ACTG (Advancing Clinical Trials Globally for HIV/AIDS and Other Infections) as well as other NIH-funded networks, investigator-initiated studies, and industry partnerships. As part of the NIH-funded SFBay Clinical Trials Unit, our ACTG site partners with BridgeHIV, which conducts HIV and STI prevention studies.
Our Research
Innovative HIV treatment strategies
We investigate novel antiretroviral approaches, including long-acting agents and broadly neutralizing antibodies. Our studies include people on their first ART regimen as well as those who are treatment-experienced. We also study interventions to reduce HIV-associated inflammation and comorbidities.
HIV cure strategies
Our research explores interventions to reduce the HIV reservoir and ultimately to stop viral replication without the need for ongoing treatment.
Sexually transmitted infections
We investigate strategies to treat and prevent sexually transmitted infections, including ongoing evaluation of community-based doxy-PEP implementation.
Viral hepatitis
Our studies evaluate optimal diagnostic and treatment approaches for HCV and HBV, with and without HIV coinfection, and include HBV cure studies.
Emerging infectious diseases
We conduct studies on treatment and prevention of emerging infectious disease, including MPOX, COVID-19, and novel respiratory pathogens.
Our Team
The SF IDRC is led by Dr. Annie Luetkemeyer, MD, who works with a dedicated team of investigators and collaborators committed to advancing clinical research and improving patient care.
Want to Get Involved?
Click here to learn more about enrolling in our open clinical studies.