Open Clinical Studies
Our active clinical research studies are a driving force behind the world-class care provided at Ward 86 and the Infectious Diseases Clinic, advancing treatment, prevention, and understanding of HIV and infectious diseases.
Explore current studies below to learn more about eligibility and how to participate:
Long-term Impact of Infection with Novel Coronavirus (LIINC)

The Long-term Impact of Infection with Novel Coronavirus (LIINC) study is a collaboration of University of California researchers looking for adult volunteers who have had a confirmed or suspected COVID-19 infection. Our team is working to understand the changes that happen after recovery from the virus.
LIINC is a team effort that connects researchers across UCSF and the United States with the goal of understanding the immune response to the virus and how it affects a person's body during recovery.
For information on enrollment, visit the LIINC website.
Study of the Consequences of the Protease Inhibitor Era (SCOPE) Study
The SCOPE Study is a long-term, observational research project at Zuckerberg San Francisco General focused on people living with and without HIV.
Its goal is to bridge clinical care and laboratory research by maintaining a diverse cohort and an extensive repository of biological specimens and clinical data. The team collaborates broadly with academic and industry partners to help advance the search for an HIV cure.
The study supports groundbreaking research, including early-phase clinical trials aimed at reducing HIV-related inflammation and the viral reservoir. SCOPE data and samples are used to study:
- Disease progression
- Natural viral control
- Immune responses
- Drug resistance
- Transmission factors
For information on enrollment, visit the SCOPE Study website or call (415) 476-4082 x140.
San Francisco Infectious Diseases Research Center (SF IDRC)

The San Francisco Infectious Diseases Research Center (SF IDRC), based in UCSF Pride Hall at Zuckerberg San Francisco General, conducts NIH- and industry-funded clinical trials to advance treatments for HIV and other infectious diseases.
Current studies focus on:
- New HIV treatments, including simplified regimens and long-acting injectable antiretroviral formulations
- Acute HIV detection and treatment
- Hepatitis treatments
- Novel treatments for addiction, infections, and chronic HIV-related inflammation
- Complications related to aging and HIV
- New approaches to measure and improve adherence to medical regimens
Click here to view the list of open clinical studies and enrollment details.